An FNA pitfall: Mammary analog secretory carcinoma mistaken for acinic cell carcinoma due to cytoplasmic granules

Intraosseous acinic cell carcinoma.

Acinic cell carcinoma is an uncommon low-grade malignant tumor of salivary glands. It was first described by Nasse in 1892, arising in parotid salivary gland. Salivary gland tumors are also known to develop within jaw bones, arising within the jaw as a primary central lesion, and are extremely rare with only a few cases reported. We present a rare case report of 65-year-old woman with intraosse...

Salivary gland acinic cell carcinoma.

Mammary analogue secretory carcinoma of salivary glands: diagnostic pitfall with distinct immunohistochemical profile and molecular features

Mammary analogue secretory carcinoma (MASC) is a newly defined entity among salivary gland malignancies which has just been established in the 4th edition of the WHO classification of head and neck tumors. MASC (synonym: secretory carcinoma) are characterized by a specific rearangement of the ETV6 gene locus. Here, we present a series of 3 MASC cases including clinical data with follow-up for u...

Primary acinic cell carcinoma of the breast.

Seven cases of this rare variant of breast carcinoma have been described in three previous publications. This paper describes an additional case, the first following chemotherapy, which in addition had an unfavourable prognosis. It also describes alterations in cell morphology, immunohistochemistry, and ultrastructure following chemotherapy.

Pure acinic cell carcinoma of the breast

Rationale:Acinic cell carcinoma (AcCC) of the breast is a rare histological type of malignant epithelial neoplasm exhibiting acinic cell differentiation. Patient concerns: A 52-year-old woman presented to the hospital with a palpable mass over the upper outer quadrant of the right breast. Diagnoses:Physical examination revealed an irregular mass in the lateral upper quadrant of the left breast,...